{"id":1822,"date":"2026-10-20T08:52:16","date_gmt":"2026-10-20T08:52:16","guid":{"rendered":"https:\/\/laseristanbulclinic.com\/eye-glossary\/exophthalmos\/"},"modified":"2026-10-20T12:56:44","modified_gmt":"2026-10-20T12:56:44","slug":"exophthalmos","status":"publish","type":"page","link":"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/exophthalmos\/","title":{"rendered":"Exophthalmos: Bulging Eyes, Causes, Symptoms and Treatment"},"content":{"rendered":"<!-- Hero (Single image) Start -->\n<section class=\"page-hero\" id=\"top\">\n\t<div class=\"phero-inner pad container-fluid\"><div class=\"row\">\n\t\t<div class=\"phero-left col-12 col-lg-7\">\n\t\t\t<div data-hero-in><ol class=\"crumbs\" aria-label=\"Breadcrumb\"><li><a href=\"https:\/\/laseristanbulclinic.com\/en\/\">Home<\/a><\/li><li><a href=\"https:\/\/laseristanbulclinic.com\/en\/eye-health\/\">Knowledge centre<\/a><\/li><li><a href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/\">Eye glossary A\u2013Z<\/a><\/li><li><span aria-current=\"page\">Exophthalmos: Bulging Eyes, Causes, Symptoms and Treatment<\/span><\/li><\/ol><\/div>\t\t\t<h1 class=\"t64 hero-title phero-title\" data-lines>Exophthalmos: Bulging Eyes, Causes, Symptoms and Treatment<\/h1>\n\t\t\t\t\t\t<p class=\"t22 phero-lead\" data-hero-in><strong>Medically reviewed by <span class=\"ph\">{{surgeon}}<\/span><\/strong>, <span class=\"ph\">{{surgeon&#8217;s title and specialty}}<\/span>, on <span class=\"ph\">{{review date}}<\/span>. Last updated <span class=\"ph\">{{date}}<\/span>.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"phero-right col-12 col-lg-5\"><figure class=\"phero-media solo\" data-hero-in><img decoding=\"async\" width=\"640\" height=\"640\" src=\"https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-light.webp\" class=\"attachment-large size-large\" alt=\"Illustration of an iris on a light background\" fetchpriority=\"high\" srcset=\"https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-light.webp 1000w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-light-300x300.webp 300w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-light-150x150.webp 150w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-light-768x768.webp 768w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\t\t\t<\/div><\/div>\n<\/section>\n<!-- Hero (Single image) End -->\n\n\n<!-- Heading (Definition card) Start -->\n<section class=\"psec pad def-sec\" id=\"definition\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\"><div class=\"def-card\" data-reveal>\n\t\t<span class=\"def-label\"><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-book\"\/><\/svg>Definition<\/span>\n\t\t\t<p class=\"def-text\"><strong>Exophthalmos<\/strong> <em>(noun; also called proptosis)<\/em>: exophthalmos is the forward bulging of one or both eyes out of the eye socket (the orbit). It happens when something inside the orbit, such as swollen muscle and fat, a growth, an infection or a blood vessel problem, takes up more room and pushes the eye forward. In adults the most common cause is thyroid eye disease, usually linked to Graves&#8217; disease, but sudden or one-sided bulging with pain, fever or lost vision is an emergency.<\/p>\n\t\t<\/div><\/div><\/div><\/div><\/section>\n<!-- Heading (Definition card) End -->\n\n\n<!-- Stats (Key facts) Start -->\n<section class=\"panel\" id=\"key-facts\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t\t<div class=\"sec-head is-center row\">\n\t\t\t\t<div class=\"col-12\"><h2 class=\"t48 sec-title\" data-reveal>Exophthalmos: key facts<\/h2><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"fact-grid row row-cols-1 row-cols-sm-2 row-cols-lg-3\" data-stagger>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-eye\"\/><\/svg><span>Other names<\/span><\/dt><dd>Proptosis, bulging eyes, protruding eyes. &#8220;Exophthalmos&#8221; comes from the Greek for &#8220;bulging eyes&#8221;<\/dd><\/dl><\/div>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-scan\"\/><\/svg><span>What it is<\/span><\/dt><dd>A sign, not a disease in itself: the eye is pushed forward because the contents of the bony orbit have increased<\/dd><\/dl><\/div>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-eye\"\/><\/svg><span>One eye or both?<\/span><\/dt><dd>Both eyes usually points to a general cause such as thyroid eye disease; one eye more often points to a local cause such as a tumour, infection or blood vessel problem<\/dd><\/dl><\/div>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-clock\"\/><\/svg><span>Most common cause in adults<\/span><\/dt><dd>Thyroid eye disease (Graves&#8217; orbitopathy)<\/dd><\/dl><\/div>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-scan\"\/><\/svg><span>How it is measured<\/span><\/dt><dd>With a Hertel exophthalmometer (a small handheld device that measures how far the front of the eye sits in front of the orbital rim), plus CT or MRI scans<\/dd><\/dl><\/div>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-warn\"\/><\/svg><span>Urgent warning signs<\/span><\/dt><dd>Sudden bulging, pain, fever, double vision, a drop in vision, or an eye that cannot close<\/dd><\/dl><\/div>\n\t\t\t\t<div class=\"col\"><dl class=\"fact-cell h-100\"><dt><svg width=\"20\" height=\"20\" aria-hidden=\"true\"><use href=\"#i-star\"\/><\/svg><span>Who treats it<\/span><\/dt><dd>An ophthalmologist (often an oculoplastic or orbital specialist) together with an endocrinologist when the thyroid is involved; at Laser Istanbul Clinic, eyelid and oculoplastic assessment is with Prof. Dr. Ahmet Sat\u0131c\u0131<\/dd><\/dl><\/div>\n\t\t\t<\/div>\n\t\t<\/div><\/div><\/div><\/section>\n<!-- Stats (Key facts) End -->\n\n\n<!-- Cards (Feature cards: 3 columns) Start -->\n<section class=\"psec pad\" id=\"what-is-exophthalmos\">\n\t<div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t\t<div class=\"sec-head is-center row\"><div class=\"col-12\"><h2 class=\"t48 sec-title\" data-reveal>What is exophthalmos?<\/h2><\/div><\/div><div class=\"prose sec-pre\"><p data-reveal>Exophthalmos is a medical term for eyes that protrude forward out of the orbit. The StatPearls medical reference describes it as the protrusion of one or both eyes anteriorly out of the orbit, caused by an increase in the contents of the bony orbit. The eye socket is a rigid cone of bone, so if its contents (the eye itself, the eye muscles, fat, nerves and blood vessels) swell or something new grows inside it, the only way out is forward.<\/p><\/div><div class=\"features row row-cols-1 row-cols-md-2 row-cols-lg-3\" data-stagger><div class=\"col\"><div class=\"feat h-100\"><span class=\"feat-icon\" aria-hidden=\"true\"><svg width=\"26\" height=\"26\" aria-hidden=\"true\"><use href=\"#i-clock\"\/><\/svg><\/span><h3>Exophthalmos or proptosis: what is the difference?<\/h3><p>In everyday medical use the two words mean the same thing. &#8220;Proptosis&#8221; is the broader, more modern term and is used for forward displacement of the eye from any cause. &#8220;Exophthalmos&#8221; is often kept for bulging caused by thyroid eye disease, but the terms are used interchangeably, and both are correct for this page.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat h-100\"><span class=\"feat-icon\" aria-hidden=\"true\"><svg width=\"26\" height=\"26\" aria-hidden=\"true\"><use href=\"#i-clock\"\/><\/svg><\/span><h3>Is it the same as having &quot;big eyes&quot; or a &quot;staring look&quot;?<\/h3><p>Not always. A person can look as though their eyes bulge when the eyelids are simply sitting too high (eyelid retraction), exposing more of the white of the eye. This is common in thyroid eye disease, where eyelid retraction occurs in up to about 90% of patients, and it can exist with or without true forward displacement of the eye. Doctors call a bulging look without real forward displacement &#8220;pseudoproptosis&#8221;. An examination and measurement tell the two apart.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat h-100\"><span class=\"feat-icon\" aria-hidden=\"true\"><svg width=\"26\" height=\"26\" aria-hidden=\"true\"><use href=\"#i-glasses\"\/><\/svg><\/span><h3>What is a normal eye position?<\/h3><p>There is no single normal number. Normal exophthalmometer readings vary with age, sex and ethnic background; a 2022 study of 1,000 North Indian adults, for example, found an average reading of 14.9 mm with a range from 8 to 22 mm, while a 2026 study of a Japanese population found an average of 15.6 mm. Because of this, doctors judge a reading against the person&#8217;s own background, compare the two eyes, and look at whether the position has changed over time. A change, or an eye that looks different from the other, matters more than one reading on its own.<\/p><\/div><\/div><\/div>\t<\/div><\/div><\/div>\n<\/section>\n<!-- Cards (Feature cards: 3 columns) End -->\n\n\n<!-- FAQ (Question and answer rows) Start -->\n<section class=\"psec pad\" id=\"what-causes-exophthalmos\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t\t<h2 class=\"t48 sec-title\" data-reveal>What causes exophthalmos?<\/h2>\n\t\t\t<p class=\"t22 sec-lead\" data-reveal>Causes fall into a few groups. Thyroid disease is by far the most common in adults.<\/p>\n\t\t\t<div class=\"prose sec-pre\"><div class=\"tbl-wrap\" data-reveal><table class=\"tbl rsp\"><thead><tr><th scope=\"col\">Cause<\/th><th scope=\"col\">How it pushes the eye forward<\/th><th scope=\"col\">Usually affects<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\"><strong>Thyroid eye disease<\/strong> (Graves&#8217; orbitopathy)<\/th><td data-label=\"How it pushes the eye forward\">The immune system inflames and swells the eye muscles, fat and connective tissue in the orbit<\/td><td data-label=\"Usually affects\">Both eyes, often unevenly; one eye sometimes<\/td><\/tr><tr><th scope=\"row\"><strong>Orbital cellulitis<\/strong><\/th><td data-label=\"How it pushes the eye forward\">A bacterial infection, often spreading from the sinuses, swells the tissue behind the eyelid<\/td><td data-label=\"Usually affects\">Usually one eye; emergency<\/td><\/tr><tr><th scope=\"row\"><strong>Orbital inflammation (non-thyroid)<\/strong><\/th><td data-label=\"How it pushes the eye forward\">Inflammation of orbital tissue without infection, sometimes related to other immune conditions<\/td><td data-label=\"Usually affects\">One or both eyes<\/td><\/tr><tr><th scope=\"row\"><strong>Tumours and growths<\/strong><\/th><td data-label=\"How it pushes the eye forward\">A benign or malignant growth in the orbit takes up space; examples include a cavernous haemangioma (a benign blood-vessel tumour)<\/td><td data-label=\"Usually affects\">Usually one eye, gradually<\/td><\/tr><tr><th scope=\"row\"><strong>Blood vessel problems<\/strong><\/th><td data-label=\"How it pushes the eye forward\">Abnormal vessels or a bleed behind the eye increase the volume or pressure in the orbit<\/td><td data-label=\"Usually affects\">Usually one eye<\/td><\/tr><tr><th scope=\"row\"><strong>Injury<\/strong><\/th><td data-label=\"How it pushes the eye forward\">Bleeding or swelling inside the orbit after trauma<\/td><td data-label=\"Usually affects\">One eye<\/td><\/tr><tr><th scope=\"row\"><strong>Other<\/strong><\/th><td data-label=\"How it pushes the eye forward\">Inherited skull and orbit conditions, and in children some tumours and cancers, including leukaemia<\/td><td data-label=\"Usually affects\">Varies<\/td><\/tr><\/tbody><\/table><\/div><\/div>\n\t\t\t<div class=\"qa-list\">\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">Thyroid eye disease: the most common cause<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>Thyroid eye disease (TED, also called Graves&#8217; ophthalmopathy or Graves&#8217; orbitopathy) is an autoimmune condition. The immune system attacks tissue around the eyes, the orbital fibroblasts become active, and the eye muscles and orbital fat swell. Several points are worth knowing:<\/p>\n<ul data-reveal>\n<li><strong>It is linked to Graves&#8217; disease.<\/strong> Graves&#8217; disease causes about 4 in 5 cases of overactive thyroid, according to the NHS. The American Thyroid Association says about one in three people with Graves&#8217; disease develop eye symptoms; EyeWiki, the American Academy of Ophthalmology&#8217;s clinical wiki, gives about half. TED can rarely occur when the thyroid blood tests are normal or low.<\/li>\n<li><strong>It affects women more than men<\/strong> (about 5 to 1 in EyeWiki&#8217;s summary), and the median age at diagnosis is 43, although it can occur from childhood to old age.<\/li>\n<li><strong>Smoking makes it more likely and more severe.<\/strong> EyeWiki calls smoking the most consistently linked risk factor, and the American Thyroid Association says secondhand smoke counts too.<\/li>\n<li><strong>It has an active and a settled phase.<\/strong> The inflammatory (active) phase lasts roughly 6 to 18 months; after that the disease settles, and the eyes improve gradually, though some changes can be permanent.<\/li>\n<li><strong>Eyes can be affected before, during or after the thyroid problem is found.<\/strong> Symptoms usually appear within the first year after Graves&#8217; diagnosis, according to the American Thyroid Association.<\/li>\n<\/ul>\n<p data-reveal>The eyes in TED often show more than bulging: eyelid retraction (up to about 90%), double vision, redness and swelling of the lids, and dryness. In a classic 1994 survey, about 60% of patients had exophthalmos and about 40% had restricted eye muscle movement.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">Orbital cellulitis: the infection you must not miss<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>Orbital cellulitis is an infection of the soft tissue behind the eyelid, most often bacterial and often spreading from the sinuses. It typically causes a bulging, painful, red and swollen eye, pain when the eye moves, and fever. EyeWiki states it needs hospital admission and intravenous antibiotics, and that with prompt treatment the outlook is excellent. Delay can be dangerous. If a bulging eye comes with fever, pain on eye movement or illness, it is an emergency, especially in a child.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">Tumours, inflammation and blood vessel problems<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>A growth in the orbit usually pushes the eye forward slowly and often on one side. Benign tumours such as cavernous haemangioma and malignant tumours both occur; imaging is needed to tell them apart. Inflammatory conditions and vascular anomalies also cause bulging, which is why a new bulge in just one eye always deserves a specialist assessment and imaging.<\/p><\/div><\/div><\/div>\n\t\t\t<\/div>\n\t<\/div><\/div><\/div><\/section>\n<!-- FAQ (Question and answer rows) End -->\n\n\n<!-- Table (Table on a dark panel) Start -->\n<section class=\"panel dark\" id=\"what-are-the-symptoms-of-exophthalmos\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t\t<h2 class=\"t48 sec-title\" data-reveal>What are the symptoms of exophthalmos?<\/h2>\n\t\t\t<p class=\"t22 sec-lead\" data-reveal>Bulging itself is the main sign, but the problems it causes in the eye are what most people notice first. Typical symptoms and signs include:<\/p>\n\t\t\t<div class=\"tbl-flow\"><div class=\"tbl-wrap\" data-reveal><table class=\"tbl rsp\"><thead><tr><th scope=\"col\">Symptom or sign<\/th><th scope=\"col\">What it can mean<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\">Eyes that look larger, more prominent or &#8220;staring&#8221;<\/th><td data-label=\"What it can mean\">Forward displacement of the eye, eyelid retraction, or both<\/td><\/tr><tr><th scope=\"row\">Gritty, dry, burning or watering eyes<\/th><td data-label=\"What it can mean\">The surface of the eye is exposed to air; dry eye and surface damage<\/td><\/tr><tr><th scope=\"row\">Redness and swelling of the eyelids, puffiness around the eyes<\/th><td data-label=\"What it can mean\">Active inflammation, as in TED<\/td><\/tr><tr><th scope=\"row\">Pain or pressure behind the eye, especially when moving it<\/th><td data-label=\"What it can mean\">Active inflammation or infection<\/td><\/tr><tr><th scope=\"row\">Double vision<\/th><td data-label=\"What it can mean\">Swollen or stiff eye muscles no longer move the eyes in step<\/td><\/tr><tr><th scope=\"row\">Eyelids that do not close fully<\/th><td data-label=\"What it can mean\">Exposure of the cornea (see below)<\/td><\/tr><tr><th scope=\"row\">Sensitivity to light<\/th><td data-label=\"What it can mean\">Surface irritation or corneal damage<\/td><\/tr><tr><th scope=\"row\">Blurred, dim or lost colour vision<\/th><td data-label=\"What it can mean\">The optic nerve may be compressed: urgent<\/td><\/tr><\/tbody><\/table><\/div><h3 data-reveal>Why exophthalmos can damage vision<\/h3>\n<p data-reveal>Two complications are the reason doctors take bulging eyes seriously:<\/p>\n<ol data-reveal>\n<li><strong>Corneal exposure.<\/strong> If the eyelids cannot close over the front of the eye (lagophthalmos), the cornea dries out and can become inflamed, ulcerated or infected. EyeWiki describes exposure keratopathy in thyroid eye disease as an ocular emergency and a major cause of vision loss.<\/li>\n<li><strong>Optic nerve compression.<\/strong> In a small number of patients (fewer than 5% in TED, according to EyeWiki), swollen tissue squeezes the optic nerve, causing dysthyroid optic neuropathy. It shows up as dimming or blurring of vision, loss of colour vision or a changed pupil reaction, and it is also an emergency that needs urgent treatment.<\/li>\n<\/ol><\/div>\t<\/div><\/div><\/div><\/section>\n<!-- Table (Table on a dark panel) End -->\n\n\n<!-- Process (Step cards: 3 columns) Start -->\n<section class=\"psec pad\" id=\"how-is-exophthalmos-diagnosed\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t<div class=\"sec-head is-center row\"><div class=\"col-12\"><h2 class=\"t48 sec-title\" data-reveal>How is exophthalmos diagnosed?<\/h2><\/div><div class=\"col-12\"><p class=\"t22 sec-lead\" data-reveal>Diagnosis answers two questions: is the eye really displaced, and what is pushing it? The steps are usually:<\/p><\/div><\/div>\t\t<ol class=\"steps row row-cols-1 row-cols-lg-3\" data-stagger>\n\t\t\t\t<li class=\"col\"><div class=\"step h-100\">\n\t\t\t\t\t\t<h3>History and examination<\/h3>\n\t\t\t\t\t\t<p>The doctor asks how long the bulging has been present, whether it is in one eye or both, and about thyroid symptoms, smoking, injury, pain and vision. They look at the position of the eyelids, eye movements, how well the eyes close, and the front of the eye with a slit lamp.<\/p>\n\t\t<\/div><\/li>\n\t\t\t\t<li class=\"col\"><div class=\"step h-100\">\n\t\t\t\t\t\t<h3>Exophthalmometry<\/h3>\n\t\t\t\t\t\t<p>A Hertel exophthalmometer measures how far each eye sits forward, in millimetres. Repeated measurements track change over time.<\/p>\n\t\t<\/div><\/li>\n\t\t\t\t<li class=\"col\"><div class=\"step h-100\">\n\t\t\t\t\t\t<h3>Vision, colour vision, pupil and visual field tests<\/h3>\n\t\t\t\t\t\t<p>These check the optic nerve and are essential if compression is suspected.<\/p>\n\t\t<\/div><\/li>\n\t\t\t\t<li class=\"col\"><div class=\"step h-100\">\n\t\t\t\t\t\t<h3>Blood tests<\/h3>\n\t\t\t\t\t\t<p>The NHS notes that a GP can arrange blood tests to assess thyroid function; an abnormal result leads to further tests to find the cause, such as thyroid antibodies.<\/p>\n\t\t<\/div><\/li>\n\t\t\t\t<li class=\"col\"><div class=\"step h-100\">\n\t\t\t\t\t\t<h3>Imaging<\/h3>\n\t\t\t\t\t\t<p>CT shows the bone and tissue density of the orbit and, in thyroid disease, the enlarged muscle bellies with the tendons spared; MRI shows how much water the tissue holds, which relates to inflammation. In any one-sided or unexplained case, imaging is how a tumour or vascular problem is found.<\/p>\n\t\t<\/div><\/li>\n\t\t\t\t<li class=\"col\"><div class=\"step h-100\">\n\t\t\t\t\t\t<h3>Clinical Activity Score (CAS)<\/h3>\n\t\t\t\t\t\t<p>In TED, doctors score signs such as pain, redness and swelling out of 7; a score of 3 or more indicates active disease, which affects treatment choice.<\/p>\n\t\t<\/div><\/li>\n\t\t\t<\/ol>\n\t\t<div class=\"sec-foot-flow prose\"><p data-reveal>Further routine measurements and scans that eye specialists use are described on our page about <a href=\"https:\/\/laseristanbulclinic.com\/en\/eye-tests-diagnostics\/\">eye examinations and diagnostic tests<\/a>.<\/p><\/div><\/div><\/div><\/div><\/section>\n<!-- Process (Step cards: 3 columns) End -->\n\n\n<!-- FAQ (Question and answer rows) Start -->\n<section class=\"psec pad\" id=\"how-is-exophthalmos-treated\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t\t<h2 class=\"t48 sec-title\" data-reveal>How is exophthalmos treated?<\/h2>\n\t\t\t<p class=\"t22 sec-lead\" data-reveal>Treatment depends on the cause. Treating the cause is first, and protecting the eye is always part of it.<\/p>\n\t\t\t\t<div class=\"qa-list\">\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">If the cause is thyroid eye disease<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>Care is shared between an endocrinologist (who manages the thyroid) and an ophthalmologist (who manages the eyes). The 2021 European guidelines (EUGOGO) group treatment by severity:<\/p><div class=\"tbl-wrap\" data-reveal><table class=\"tbl rsp\"><thead><tr><th scope=\"col\">Severity<\/th><th scope=\"col\">Typical approach<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\"><strong>Mild<\/strong><\/th><td data-label=\"Typical approach\">Control risk factors (stop smoking, keep thyroid levels stable), lubricating drops, and selenium supplements in areas where selenium intake is low; many mild cases settle with time<\/td><\/tr><tr><th scope=\"row\"><strong>Moderate to severe, active<\/strong><\/th><td data-label=\"Typical approach\">Intravenous methylprednisolone (a steroid) in 12 weekly infusions, 4.5 g in total, usually with mycophenolate; further options include orbital radiotherapy and biologic drugs<\/td><\/tr><tr><th scope=\"row\"><strong>Sight-threatening<\/strong> (optic nerve compression, corneal breakdown)<\/th><td data-label=\"Typical approach\">High-dose intravenous steroid at once and, if there is no quick response, urgent orbital decompression surgery<\/td><\/tr><tr><th scope=\"row\"><strong>Settled disease with leftover changes<\/strong><\/th><td data-label=\"Typical approach\">Rehabilitative surgery<\/td><\/tr><\/tbody><\/table><\/div><p data-reveal>Some details:<\/p>\n<ul data-reveal>\n<li><strong>Smoking and thyroid control.<\/strong> EyeWiki states that stopping smoking and keeping the thyroid level normal (&#8220;euthyroid&#8221;) help prevent worsening and shorten the active phase. The EUGOGO guideline also lists radioactive iodine treatment of the thyroid as a risk factor to discuss with your endocrinologist.<\/li>\n<li><strong>Self-care.<\/strong> The American Thyroid Association lists sunglasses, lubricating drops and sleeping with the head raised.<\/li>\n<li><strong>Teprotumumab.<\/strong> In 2020 the US FDA approved this drug (Tepezza), an IGF-1 receptor blocker given as eight intravenous infusions three weeks apart. In the 2020 NEJM trial, 83% of patients on teprotumumab had a meaningful reduction in proptosis at week 24 versus 10% on placebo. The FDA label lists hearing impairment, high blood sugar and bowel inflammation among its warnings, and requires contraception during treatment and for 6 months after. It is prescribed by specialists, and availability varies by country.<\/li>\n<li><strong>Orbital decompression.<\/strong> A surgeon removes bone or fat to give the eye more room. In a 2026 study of secondary decompression, average eye position fell by 4.5 mm; 5 of 17 patients developed new double vision, a known risk of the operation.<\/li>\n<li><strong>Order of surgery.<\/strong> After the disease has settled, EyeWiki advises an order: orbital decompression first, then eye-muscle (squint) surgery for double vision, then eyelid surgery for retraction or exposure, because each step changes the next.<\/li>\n<\/ul><\/div><\/div><\/div>\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">If the cause is infection<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>Orbital cellulitis is treated in hospital with intravenous antibiotics, and surgery if an abscess forms or antibiotics do not work within 24 to 48 hours (EyeWiki).<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">If the cause is a tumour, inflammation or a vessel problem<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>Treatment follows the diagnosis: observation of a harmless growth, surgery, medication such as steroids for non-infectious inflammation, or radiotherapy and other cancer treatment. This is directed by an orbital specialist after imaging, and often a biopsy.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"qa-row\" data-reveal><div class=\"row\"><h3 class=\"qa-q col-12 col-lg-4\">Protecting the eye while it is treated<\/h3><div class=\"qa-a prose col-12 col-lg-8\"><p data-reveal>Whatever the cause, doctors protect the cornea first: preservative-free lubricating drops by day, ointment at night, taping or other measures when the lids do not close, and treatment of any eyelid retraction. Our team deals with the eyelid side of these problems.<\/p>\n<p data-reveal><strong>Treatment with us:<\/strong> if your bulging eyes come with eyelid problems (a high, retracted lid, a lid that will not close, or a lid position that has changed), eyelid and oculoplastic surgery is led by Prof. Dr. Ahmet Sat\u0131c\u0131. Thyroid control stays with your own endocrinologist, and a bulging eye that is new, painful or one-sided needs a local emergency assessment first. Send us your reports and scans and the surgeon will tell you whether treatment in Istanbul is right for you.<\/p><div class=\"links-row\" data-reveal><a class=\"link-arrow\" href=\"https:\/\/laseristanbulclinic.com\/en\/free-consultation\/\">Free online consultation: upload your prescription and scans <svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-arrow\"\/><\/svg><\/a><\/div><\/div><\/div><\/div>\n\t\t\t<\/div>\n\t<\/div><\/div><\/div><\/section>\n<!-- FAQ (Question and answer rows) End -->\n\n\n<!-- Image + Text (Image left, text right) Start -->\n<section class=\"psec pad split-sec\" id=\"when-to-see-a-doctor-about-bulging-eyes\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\"><div class=\"split\"><div class=\"row\">\n\t\t<div class=\"split-media col-12 col-lg-6\" data-reveal><div class=\"media\" data-parallax><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"640\" src=\"https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-dark-1024x1024.webp\" class=\"attachment-large size-large\" alt=\"Illustration of an iris on a dark background\" sizes=\"auto, (max-width: 991px) 100vw, 50vw\" srcset=\"https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-dark-1024x1024.webp 1024w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-dark-300x300.webp 300w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-dark-150x150.webp 150w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-dark-768x768.webp 768w, https:\/\/laseristanbulclinic.com\/wp-content\/uploads\/2026\/10\/eye-iris-illustration-dark.webp 1400w\" \/><\/div><\/div>\n\t\t<div class=\"split-copy col-12 col-lg-6\">\n\t\t\t\t\t\t<h2 class=\"t48\" data-reveal>When to see a doctor about bulging eyes<\/h2>\n\t\t\t\t\t\t\t\t<div class=\"prose\" data-reveal><div class=\"list-card\" data-reveal><h3>Seek emergency care the same day if you or your child have:<\/h3><ul class=\"check-list\"><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>sudden bulging of an eye, or bulging with pain, fever, or a red, swollen eyelid<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>pain when you move the eye<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>a drop in vision, dimming or loss of colour vision<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>new double vision with eye bulging<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>an eye that will not close, with pain or redness<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>bulging after a head or eye injury<\/span><\/li><\/ul><\/div><div class=\"list-card\" data-reveal><h3>Book an appointment soon (within days to weeks) if:<\/h3><ul class=\"check-list\"><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>your eyes have gradually become more prominent, or one eye looks different from the other<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>you have an overactive thyroid or Graves&#8217; disease and develop dry, gritty, red or puffy eyes<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>friends or family comment that your eyes look &#8220;staring&#8221; and you are not sure why<\/span><\/li><li><svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-check\"\/><\/svg><span>you smoke and have thyroid disease and eye symptoms: ask for help to stop, because it affects your eyes<\/span><\/li><\/ul><\/div><p data-reveal>If you already have a diagnosis and want a second opinion on eyelid or surgical options, you can send your scans for review before you travel.<\/p><\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/section>\n<!-- Image + Text (Image left, text right) End -->\n\n\n<!-- FAQ (FAQ accordion) Start -->\n<section class=\"faq pad\" id=\"faq\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\"><div class=\"faq-grid\">\n\t<div class=\"faq-side\">\n\t\t\t\t<h2 class=\"t48\" data-reveal>Frequently asked questions<\/h2>\n\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"acc\" data-stagger>\n\t\t\t\t<div class=\"acc-item is-open\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"true\" aria-controls=\"faq-6a7f86bf-a1\" id=\"faq-6a7f86bf-q1\">What is exophthalmos?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a1\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q1\"><div class=\"acc-body\"><p data-reveal>Exophthalmos is the medical term for one or both eyes bulging forward out of the eye socket. It is a sign of another problem, most often thyroid eye disease in adults, and the word means the same as proptosis.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a2\" id=\"faq-6a7f86bf-q2\">What is the difference between exophthalmos and proptosis?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a2\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q2\"><div class=\"acc-body\"><p data-reveal>In practice there is none. Proptosis is the more general term for any forward displacement of the eye, while exophthalmos is often used when the cause is thyroid disease. Doctors use them interchangeably.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a3\" id=\"faq-6a7f86bf-q3\">What causes bulging eyes?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a3\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q3\"><div class=\"acc-body\"><p data-reveal>Thyroid eye disease, linked to Graves&#8217; disease, is the most common cause in adults. Others include orbital infection (orbital cellulitis), orbital tumours, non-infectious orbital inflammation, blood vessel problems and injury. In one-sided cases the cause is more often local, which is why imaging is needed.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a4\" id=\"faq-6a7f86bf-q4\">Can exophthalmos be cured?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a4\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q4\"><div class=\"acc-body\"><p data-reveal>It depends on the cause. Infections can resolve fully with prompt treatment, and mild thyroid eye disease often settles on its own as the disease passes its active phase. When changes remain, they can be improved with medication or surgery, but results vary and no outcome can be promised.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a5\" id=\"faq-6a7f86bf-q5\">Is exophthalmos an emergency?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a5\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q5\"><div class=\"acc-body\"><p data-reveal>Sometimes. Sudden bulging, pain, fever, double vision or reduced vision can mean orbital cellulitis or optic nerve compression, and need same-day assessment. A slow change in the appearance of the eyes should be checked within days to weeks.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a6\" id=\"faq-6a7f86bf-q6\">Is exophthalmos always caused by a thyroid problem?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a6\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q6\"><div class=\"acc-body\"><p data-reveal>No. Thyroid eye disease is the most common cause in adults, but infection, tumours, inflammation, blood vessel problems and injury also cause it. A person can also have a &#8220;staring&#8221; look from eyelid retraction without the eye being pushed forward at all (pseudoproptosis).<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a7\" id=\"faq-6a7f86bf-q7\">Does smoking make bulging eyes worse?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a7\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q7\"><div class=\"acc-body\"><p data-reveal>Yes. Smoking is the best-documented risk factor for developing thyroid eye disease and for it becoming more severe, and secondhand smoke also counts. Stopping smoking is one of the most useful things a person with thyroid eye disease can do.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a8\" id=\"faq-6a7f86bf-q8\">Can bulging eyes affect eyesight?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a8\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q8\"><div class=\"acc-body\"><p data-reveal>They can. An eye that does not close fully can develop corneal damage, and in a small number of people with thyroid eye disease the optic nerve is compressed. Both are treatable if found early, which is why sudden changes in vision should be seen urgently.<\/p><\/div><\/div><\/div>\n\t\t\t\t<div class=\"acc-item\"><h3><button type=\"button\" class=\"t32\" aria-expanded=\"false\" aria-controls=\"faq-6a7f86bf-a9\" id=\"faq-6a7f86bf-q9\">Which doctor treats exophthalmos?<svg width=\"24\" height=\"24\" aria-hidden=\"true\"><use href=\"#i-plus\"\/><\/svg><\/button><\/h3><div class=\"acc-panel\" id=\"faq-6a7f86bf-a9\" role=\"region\" aria-labelledby=\"faq-6a7f86bf-q9\"><div class=\"acc-body\"><p data-reveal>Usually an ophthalmologist, often with oculoplastic or orbital training, working with an endocrinologist if the thyroid is involved. Eyelid and oculoplastic surgery at Laser Istanbul Clinic is led by Prof. Dr. Ahmet Sat\u0131c\u0131.<\/p><\/div><\/div><\/div>\n\t\t\t<\/div>\n\t<\/div><\/div><\/div><\/div><script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What is exophthalmos?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Exophthalmos is the medical term for one or both eyes bulging forward out of the eye socket. It is a sign of another problem, most often thyroid eye disease in adults, and the word means the same as proptosis.\"}},{\"@type\":\"Question\",\"name\":\"What is the difference between exophthalmos and proptosis?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"In practice there is none. Proptosis is the more general term for any forward displacement of the eye, while exophthalmos is often used when the cause is thyroid disease. 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Eyelid and oculoplastic surgery at Laser Istanbul Clinic is led by Prof. Dr. Ahmet Sat\u0131c\u0131.\"}}]}<\/script><\/section>\n<!-- FAQ (FAQ accordion) End -->\n\n\n<!-- Cards (Feature cards: 3 columns) Start -->\n<section class=\"psec pad\" id=\"related-terms\">\n\t<div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\">\n\t\t<div class=\"sec-head is-center row\"><div class=\"col-12\"><h2 class=\"t48 sec-title\" data-reveal>Related terms<\/h2><\/div><\/div><div class=\"features row row-cols-1 row-cols-md-2 row-cols-lg-3\" data-stagger><div class=\"col\"><div class=\"feat rel h-100\"><h3>Proptosis<\/h3><p>the broader term for forward displacement of the eye from any cause.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Thyroid eye disease (Graves&#039; orbitopathy)<\/h3><p>autoimmune inflammation of the tissue around the eyes; the most common cause of exophthalmos in adults.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Enophthalmos<\/h3><p>the opposite: the eye sits sunken back in the orbit.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Eyelid retraction<\/h3><p>an upper lid that sits too high, giving a staring look.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Lagophthalmos<\/h3><p>incomplete closure of the eyelids.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Orbit<\/h3><p>the bony socket that holds the eye.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Orbital cellulitis<\/h3><p>infection of the tissue behind the eyelid; an emergency.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3>Exophthalmometer<\/h3><p>the instrument used to measure how far the eye protrudes.<\/p><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3><a href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/ptosis\/\">Ptosis<\/a><\/h3><p>the opposite lid problem, a drooping upper eyelid.<\/p><a class=\"feat-go\" href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/ptosis\/\" tabindex=\"-1\" aria-hidden=\"true\">Read more <svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-arrow\"\/><\/svg><\/a><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3><a href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/entropion-and-ectropion\/\">Entropion and ectropion<\/a><\/h3><p>lid margins turned in or out, which can also irritate the eye surface.<\/p><a class=\"feat-go\" href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/entropion-and-ectropion\/\" tabindex=\"-1\" aria-hidden=\"true\">Read more <svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-arrow\"\/><\/svg><\/a><\/div><\/div><div class=\"col\"><div class=\"feat rel h-100\"><h3><a href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/\">Eye glossary A\u2013Z<\/a><\/h3><a class=\"feat-go\" href=\"https:\/\/laseristanbulclinic.com\/en\/eye-glossary\/\" tabindex=\"-1\" aria-hidden=\"true\">Read more <svg width=\"18\" height=\"18\" aria-hidden=\"true\"><use href=\"#i-arrow\"\/><\/svg><\/a><\/div><\/div><\/div>\t<\/div><\/div><\/div>\n<\/section>\n<!-- Cards (Feature cards: 3 columns) End -->\n\n\n<!-- List (Sources and medical review) Start -->\n<section class=\"psec pad tight\"><div class=\"container-fluid px-0\"><div class=\"row g-0\"><div class=\"col-12\"><details class=\"sources\" data-reveal><summary class=\"t22\">Sources for the facts on this page<\/summary><ol>\n\t\t<li>Exophthalmos. <em>StatPearls<\/em> (NBK559323), NCBI Bookshelf. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK559323\/ (definition; checked through Europe PMC record PMID 32644749)<\/li>\n\t\t<li>EyeWiki (AAO). Thyroid Eye Disease. https:\/\/eyewiki.org\/Thyroid_Eye_Disease<\/li>\n\t\t<li>EyeWiki (AAO). Orbital Cellulitis. https:\/\/eyewiki.org\/Orbital_Cellulitis<\/li>\n\t\t<li>American Thyroid Association. Thyroid Eye Disease. https:\/\/www.thyroid.org\/thyroid-eye-disease\/<\/li>\n\t\t<li>NHS. Overactive thyroid (hyperthyroidism). https:\/\/www.nhs.uk\/conditions\/overactive-thyroid-hyperthyroidism\/<\/li>\n\t\t<li>Bartalena L, Kahaly GJ, Baldeschi L, et al. The 2021 European Group on Graves&#8217; Orbitopathy (EUGOGO) clinical practice guidelines for the medical management of Graves&#8217; orbitopathy. <em>Eur J Endocrinol<\/em> 2021;185(4):G43\u2013G67. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/34297684\/<\/li>\n\t\t<li>Douglas RS, Kahaly GJ, Patel A, et al. Teprotumumab for the treatment of active thyroid eye disease. <em>N Engl J Med<\/em> 2020;382:341\u2013352. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/31971679\/<\/li>\n\t\t<li>US FDA. Tepezza (teprotumumab-trbw) prescribing information. https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/761143s000lbl.pdf<\/li>\n\t\t<li>Bartley GB. Ophthalmopathy associated with autoimmune thyroid disease. <em>Trans Am Ophthalmol Soc<\/em> 1994. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/7886878\/<\/li>\n\t\t<li>Revankar S, Mehta A. Determination of exophthalmometry values in the North Indian population. <em>Indian J Ophthalmol<\/em> 2022. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/35918977\/<\/li>\n\t\t<li>Nakaji E, et al. Exophthalmometry values of a contemporary Japanese population with\/without Graves&#8217; disease. <em>Endocr J<\/em> 2026. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/41297932\/<\/li>\n\t\t<li>Cheng et al. Secondary inferomedial orbital decompression. <em>Indian J Ophthalmol<\/em> 2026. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/42671097\/<\/li>\n\t\t<li>Abidin NA, Ismail IA, Jamil SN, Mustafa N. When patients present with bulging eyes: a case series of proptosis. <em>Malays Fam Physician<\/em> 2025. PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/40662124\/<\/li>\n\t<\/ol><\/details><\/div><\/div><\/div><\/section>\n<!-- List (Sources and medical review) End -->\n\n\n<!-- Call to Action (Assessment band) Start -->\n<section class=\"cta-band\" id=\"assessment\">\n\t<div class=\"contact-bg\" aria-hidden=\"true\"><span><\/span><span><\/span><span><\/span><\/div>\n\t<div class=\"cta-inner pad container-fluid\"><div class=\"row\">\n\t\t<div class=\"col-12 col-lg-7\"><div class=\"cta-copy\">\n\t\t\t\t\t\t<h2 class=\"t64\" data-reveal>Bulging eyes or eyelid changes you are worried about?<\/h2>\n\t\t\t\t\t\t<p class=\"t22\" data-reveal>Send us your reports, scans and a few photos. 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